Kinase Inhibitors

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Medical Markets:

Business Communications Company Inc.
Market Study January 2006

Table of Contents

INTRODUCTION

Human protein kinases are intriguing drug targets, in part because they regulate a wide variety of signaling pathways and include over 500 distinct protein molecules. Synthetic inhibitors of protein kinases include small molecules that may be easily administered as oral therapeutic compounds. These inhibitors can rapidly and often specifically alter the activation state of a target kinase. They further have significant potential in the clinical treatment of major diseases including cancer, heart disease, inflammatory disorders, diabetes, macular degeneration, and neurological disorders.

This BCC study determines the current status of the kinase inhibitor industry and assesses its growth potential. Only a handful such therapeutics have entered clinical use as of 2005. For each, BCC examined the drug development process, major challenges and achievements and where applicable, the projected market for each of these drugs through 2010.

Of particular interest are up-and-coming kinase inhibitors in clinical trials and preclinical development. Leading candidates are identified in each kinase inhibitor class by molecular target and by disease application. The result is a comprehensive analysis of the current market and its future direction.

SCOPE OF STUDY

The report contains:

- A thorough review of the technologies employed in the kinase inhibitor

- Analysis of the evidence of efficacy and technical limitations of each kinase inhibitor type in clinical use

- Analysis of the current market status and growth forecasts through 2010 for each kinase inhibitor

- Examination of the potential for additional novel applications

Discussion of the role of government regulations, recent patents and factors affecting the industry worldwide
Analysis of how the development of new kinase inhibitors is translating into new medical therapies for specific disease

For full details, please email jenniferc@cmsinfo.com

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